Alpha-2-Macroglobulin (A2M) Therapy
Stop Cartilage Breakdown and Joint Inflammation at the Source
Based on verified Google reviews•Verified Business Profile
Eleonora Grange
2 weeks ago
“Dr. J and Susan ARE AMAZING!! Great people to work with, very professional. My knee pain had gotten so bad... tried PRP & Stem Cell treatment and it's like night and day, no more excruciating pain!”
Patty Fiorini
3 weeks ago
“After having PRP and stem cell injection treatment, my knee doesn't have that achey arthritic pain any longer. Highly recommend working with Dr J and Susan.”
EDZEL PETER BARRETT
a month ago
“Dr. J and Susan helped me out a lot with my back and shoulder. Had PRP injection and now I can freely move my arms without pain!”
Dana Stoddard
a month ago
“I entered the world of A2M and Advanced Injection Therapy! The effects were immediate and I am able to stride normally and the pain is gone!”
Ariel Tapia
2 months ago
“Since my PRP treatment at True Health Medical I have no pain. It worked just about immediately. 1000% recommend doing it!”
Chad Gannon
2 months ago
“I had regenerative treatment for a partial rotator cuff tear. It's been a year and I cannot say the last time I felt pain in my shoulder. The treatment works!”
Seven Spears Martial Arts
3 months ago
“Started going to Susan and Dr. J for chronic low back pain, did the PRP therapy and a few months later my back pain is essentially gone.”
Jeri Simpson
4 months ago
“I don't think I can speak positively enough about True Health! They genuinely care about their patients and are just all around good people.”
Maxine Lewis
5 months ago
“Injections for both my knees and noticed a huge difference just a week later. My knees don't grind anymore and pain is almost nonexistent!”
Robert K.
6 months ago
“Great experience with True Health Medical. The staff is welcoming, attentive, and really focused on treating the root cause of the pain rather than masking symptoms.”
Eleonora Grange
2 weeks ago
“Dr. J and Susan ARE AMAZING!! Great people to work with, very professional. My knee pain had gotten so bad... tried PRP & Stem Cell treatment and it's like night and day, no more excruciating pain!”
Patty Fiorini
3 weeks ago
“After having PRP and stem cell injection treatment, my knee doesn't have that achey arthritic pain any longer. Highly recommend working with Dr J and Susan.”
EDZEL PETER BARRETT
a month ago
“Dr. J and Susan helped me out a lot with my back and shoulder. Had PRP injection and now I can freely move my arms without pain!”
Dana Stoddard
a month ago
“I entered the world of A2M and Advanced Injection Therapy! The effects were immediate and I am able to stride normally and the pain is gone!”
Ariel Tapia
2 months ago
“Since my PRP treatment at True Health Medical I have no pain. It worked just about immediately. 1000% recommend doing it!”
Chad Gannon
2 months ago
“I had regenerative treatment for a partial rotator cuff tear. It's been a year and I cannot say the last time I felt pain in my shoulder. The treatment works!”
Seven Spears Martial Arts
3 months ago
“Started going to Susan and Dr. J for chronic low back pain, did the PRP therapy and a few months later my back pain is essentially gone.”
Jeri Simpson
4 months ago
“I don't think I can speak positively enough about True Health! They genuinely care about their patients and are just all around good people.”
Maxine Lewis
5 months ago
“Injections for both my knees and noticed a huge difference just a week later. My knees don't grind anymore and pain is almost nonexistent!”
Robert K.
6 months ago
“Great experience with True Health Medical. The staff is welcoming, attentive, and really focused on treating the root cause of the pain rather than masking symptoms.”
What Is A2M Therapy?
Alpha-2-Macroglobulin (A2M) is a powerful, naturally occurring protein found in your blood that acts as your body's chief defender against destructive cartilage-destroying enzymes.
In osteoarthritis and chronic joint degeneration, harmful catabolic enzymes attack cartilage cells, causing steady pain, stiffness, and breakdown. Scientists refer to A2M as a "master inhibitor" because it binds to these destructive enzymes and permanently neutralizes them before they can damage your joints1.
At True Health Medical San Diego, our integrative medical team utilizes high-concentration autologous A2M to protect joint cartilage, relieve deep inflammation, and help patients maintain active, pain-free lives without invasive surgery.
EmCyte® Technology
Ultra-pure dual-spin concentration
How A2M Therapy Works
Our simple, 3-step in-office procedure turns your body's own natural defenses into targeted joint protection.
In-Office Blood Draw
A routine, small blood sample is collected right here in our San Diego clinic.
Advanced Dual-Spin Separation
Using our state-of-the-art EmCyte dual-spin centrifuge system, we isolate and super-concentrate the A2M master protein.
Targeted Precision Injection
The concentrated A2M compound is precisely injected into the affected joint using imaging guidance for maximum therapeutic accuracy.
Goal: Stop active cartilage breakdown, calm chronic inflammation, and restore natural joint function.
A2M as a Preparation Tool for Regenerative Therapies
In addition to being a standout standalone solution, A2M is often used by our medical team to prime and optimize the joint environment prior to administering other regenerative procedures, including:
- Platelet-Rich Plasma (PRP) Therapy
- Trigger Point & Joint Rehabilitation
- Targeted Viscosupplementation
By clearing out destructive enzymes and lowering inflammatory toxic load first, A2M creates a fertile, healthy microenvironment that enables follow-up regenerative treatments to work far more effectively1.
Why Choose A2M Over Cortisone Injections?
While traditional corticosteroid injections offer temporary symptom relief, studies show repeated cortisone can actually accelerate cartilage degeneration over time.
Steroid Injections
Temporary pain masking • May weaken tendons & accelerate cartilage loss over time
Autologous A2M Therapy
Natural protein from your blood • Halts cartilage damage • No risk of allergic reaction or drug toxicity1
Conditions Treated
A2M injections are particularly effective for early to moderate joint degeneration across multiple areas:
- Knee, hip, and shoulder osteoarthritis
- Spinal facet joint arthritis
- Degenerative disc disease
- Cartilage damage from sports or overuse injuries
- Chronic joint inflammation & stiffness
Who Is a Good Candidate?
You may be an ideal candidate for A2M Joint Therapy if you have:
- Early-stage or moderate osteoarthritis or chronic joint discomfort
- Joint pain that hasn't responded to rest, physical therapy, or NSAIDs
- A desire to avoid steroid injections, habit-forming drugs, or invasive surgery
- An active San Diego lifestyle limited by stiffness or nagging joint pain
Key Benefits of A2M Therapy
How EmCyte® Dual-Spin Technology Improves Your Results
At True Health Medical San Diego, we utilize EmCyte's advanced dual-spin processing system. Unlike single-spin or lower-yield wax separators, EmCyte technology delivers significantly higher purity and concentration of active A2M proteins. This ensures maximum biological activity and optimal protection for your joint cartilage1.
Scientific References & Medical Literature
Visit True Health Medical San Diego
Ready to find lasting joint relief without surgery? Contact our office today to schedule your A2M consultation with our clinical team.